Evidence Grading Explained

Every claim on this wiki is labelled by evidence strength so you can weigh it. The four tiers:

TierMeaning
ApprovedRegulator-approved for an indication (e.g. semaglutide for weight management).
ClinicalHuman trials exist — we note size and quality (a 12-person study is not a 1,200-person one).
PreclinicalAnimal or in-vitro data only. Most “healing” peptide claims sit here.
AnecdotalCommunity-reported; no controlled data.

We also flag when findings trace to a single research group or lack independent replication. This scheme is applied in each peptide page’s Evidence by Outcome table and as inline tags.


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